Palladium nano crystalline electrode development for electrical impedance spectroscopy application
Wei Chen1*, Chien-Hao Su2, Peng-Jen Chen1, Guo-Cheng Hsu2, Chia-Ching Chang1,3
1Department of Biological Science and Technology, National Chiao Tung University, Hsinchu, Taiwan
2Cheeshin Technology Co, Jhunan, Taiwan
3Institute of Physics, Academia Sinica, Nankang, Taiwan
* presenting author:Wei Chen,
Electrochemical analysis is a sensitivity and selectivity technique which can detect the intermolecular. Gold block based electrode provides good electron transfer kinetics and has been widely used in electrochemical analysis. However, gold electrode is expensive and time consuming. In this study, we have developed a novel nano crystalline palladium (Pd) electrode by sputtering method on a flexible polyethylene terephthalate (PET) substrate. This novel electrode can effectively detect redox reactions as good as gold electrode in electrolyte by CV analysis. Our data indicated that the gold electrode can be replaced by our nano crystalline Pd electrode in electrochemical analysis. Furthermore, we will use this novel electrode to detect DNA and drug interaction by electrical impedance spectroscopy (EIS) at sub-nanogram level.

Keywords: Nano crystalline electrode, Electrical Impedance Spectroscopy (EIS), DNA- drug interaction